"How are you doing?" is the short and simple way to ask "Are you doing well?" in English. This question is a common way to show interest in someone's life and well-being. It can be used in any context, from casual conversation to more formal situations. The question can be answered with phrases such as "I'm good, thanks for asking" or "Not so great, but I'm working on it." The answer will depend on the person's current situation and mood.